CARDIAC SAFETY STUDIES

Cardiac safety (pharmaceutical vs. toxicity) of experimental compounds developed for non-cardiac pathologies such as cancer and diabetes is crucial, requiring rigorous testing using not only cell lines, but also healthy organs.

AVIVA’s tissue physiology group has developed various models, including in vitro human tissue assays, that allow for testing of multiple heart functions.

Early assessment of the cardiac safety of compounds can conveniently be established based on the output of the study report provided by AVIVA.